Non-Acetaminophen Induced Acute Liver Failure of Viral etiology: Treatment with and without NAcetylcysteine; comparing the length of hospital stay and survival status in children at the tertiary care hospital




ABSTRACT

Acetaminophen poisoning is a common cause of acute liver failure (ALF) and is treated with N-Acetylcysteine (NAC), which acts as an antidote, antioxidant and anti-inflammatory agent. NAC role in non-acetaminophen induced acute liver failure among children remains controversial and a few centers have adopted this option. Viral hepatitis (A and E) remains the leading cause of ALF in Pakistan. We aim to determine the role of NAC in ALF secondary to viral etiology.